Table 3.
Genetic correlation between social interaction and other anxiety-like behavior
| Contact duration | Contact frequency | Genital grooming | Social sniffing | Following | Aggressive behaviors | ||
|---|---|---|---|---|---|---|---|
| Factor 1 | General locomotor activity | −0.578 (P = 0.006**) | 0.647 ( P = 0.002**) | −0.309 (P = 0.172) | −0.245 (P = 0.284) | 0.001 (P = 0.996) | −0.032 (P = 0.890) |
| Factor 2 | Thigmotaxis | 0.417 (P = 0.060) | −0.232 (P = 0.311) | 0.132 (P = 0.569) | 0.371 (P = 0.098) | 0.105 (P = 0.651) | 0.146 (P = 0.527) |
| Factor 3 | EP open-arm exploration | 0.282 (P = 0.216) | 0.111 (P = 0.632) | 0.433 (P = 0.050*) | 0.157 (P = 0.497) | 0.372 (P = 0.097) | 0.328 (P = 0.147) |
| Factor 4 | Risk assessment | −0.296 (P = 0.193) | −0.144 (P = 0.532) | −0.166 (P = 0.473) | −0.177 (P = 0.443) | −0.052 (P = 0.821) | 0.045 (P = 0.848) |
| Factor 5 | Autonomic emotionality | 0.727 ( P < 0.001**) | − 0.661 ( P = 0.001**) | 0.503 (P = 0.020*) | 0.374 (P = 0.095) | 0.090 (P = 0.695) | 0.170 (P = 0.461) |
The factor scores for anxiety-like behavior were obtained from Takahashi et al. (2008), in which the group size for males of each consomic strain and B6 ranged from 15 to 25. Genetic correlations of r > 0.60 are in bold, and r < 0.30 are in italics. EP open-arm exploration is a factor contributed mainly by the elevated plus-maze test. P values are provided in parentheses
** P < 0.01, * P < 0.05