Table 5.

Summary of results for the top 10 genes in order from PDgene (June 2009) for each GWAS dataset for the SNP in each gene with the smallest joint analysis p-value.

Gene	SNP	PM	PC	PN	P3	#SNPs in gene	Gene Size (bp)
GBA	rs9628662	0.694	0.165	0.581	0.153	1	10,245
LRRK2	rs1907632	0.423	0.255	0.023	0.032	42	144,273
SNCA	rs2736990	5.08×10−5	8.67×10−4	0.102	6.70×10−8	15	112,876
PINK1	rs2296223	0.546	0.031	0.247	0.212	2	18,056
MAPT	rs1981997	4.96×10−3	1.37×10−4	0.733	2.50×10−6	15	134,002
USP24	rs12065953	8.96×10−3	0.195	0.129	7.81×10−3	2	149,006
CYP2D6	rs769258	0.572	0.848	0.033	0.574	1	4,382
MAOB	rs209766	0.031	0.172	0.056	0.003	31	115,864
ELAVL4	rs17105974	3.39×10−3	0.059	0.142	0.042	10	153,854
APOE	rs439401	0.568	0.411	0.829	0.41	2	3,611

P_M – p-values from the MIHG GWAS

P_C – p-values from the CIDR GWAS

P_N – p-values from the NINDS GWAS

P₃ – p-values from the joint analysis of the three GWAS