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. 2009 Jun;25(6):583–601. doi: 10.1089/aid.2008.0240

FIG. 3.

FIG. 3.

Comparison of Env V1 region group percentages between tissues harvested from pigtailed macaques 5 or 7 days postinfection and SIVsmmFGb stock virus. Env V1 amino acid sequences obtained from the SIVsmmFGb stock virus were aligned and grouped as shown in Fig. 1. Env V1 amino acid sequences from tissues were grouped as described in Materials and Methods. The percentage of sequences in each group from each tissue was determined for each animal and averaged to yield a mean percentage for each group in each tissue across all animals. The percentage of each group in the SIVsmmFGb stock virus was compared statistically with the mean percentage of each group in the tissues, using the Mann–Whitney rank-sum test. Statistically significant differences (p < 0.05) are noted. Error bars represent 1 standard error. Results for (A) axillary lymph node, (B) basal ganglia, (C) hippocampus, and (D) midfrontal cortex; cerebellum and mesenteric lymph node results are shown in Supplementary Fig. 1. Tissues indicated by asterisks (***) lack data from PQo1; results are thus the average of the remaining five animals.