Table 1.
Survival Time, Plasma/CSF Viral Load, and CD4+ T Cell Count
|
|
Viral load (× 104 RNA copies/ml) |
|
|
---|---|---|---|---|
Macaque | Survivala(weeks, pi) | Plasma | CSF | CD4+ T cellsb |
Morphine-dependent | ||||
1/04L | 18 | 3,340 | 226 | 3 |
1/42Nc | 19 | 107,000 | 111 | 10 |
1/28Qc | 20 | 7660 | 166 | 6 |
Control | ||||
2/02P | 60 | 2.56 | 1.67 | 42 |
2/AC42 | 64 | 0.038 | NDd | 67 |
2/31P | 147 | 0.236 | NDd | 503 |
A monkey surviving <24 weeks after infection was considered a rapid disease progressor.
CD4+ T cells are presented as number/μl of blood at the time of necropsy.
The animal developed neurological disorders.
Not detectable. The viral load was <20 RNA copies/ml.