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Recovery of HIV from Resting CD4+ T Cells Isolated from Aviremic, ART-Treated, HIV-Infected Individuals after a 3- or 6-h Pulsed Exposure to SAHA Compared to 24 h Exposure to Maximal Mitogen Activation
|
Infected units per billion resting CD4+ T cells | ||
|---|---|---|
| Patients | SAHAa | Maximal mitogenb |
| 6 | 162 (3 h) | 1160 (24 h) |
| 7 | 295 (6 h) | 360 (24 h) |
Patient 6 250 nM SAHA; patient 7 335 nM SAHA.
PHA 1 μg/ml, IL-2 100 U/ml, 5-fold excess irradiated allogeneic cells.
