Table 5.
Demographics [mean (SD)] and distribution [number (%)] with clinically possible AD in community compared to clinic cohorts
| Community cohorts |
Clinical cohort |
|
|---|---|---|
| Number | 42 | 46 |
| Age at death | 87.2 (SD = 6.6) | 81.3 (SD = 6.3) |
| Education | 16.9 (SD = 3.1) | 14.3 (SD = 3.5) |
| MMSE | 13.4 (SD = 8.4) | 5.8 (SD = 7.5) |
| Pathologic diagnosis of AD (NIA-Reagan) |
24 (57.1%) | 41 (89.1%) |
| High | 7 (16.7%) | 27 (58.7%) |
| Intermediate | 17 (40.5%) | 14 (30.4%) |
| Infarcts (any) | 28 (66.7%) | 19 (41.3%) |
| Macroscopic | 27 (64.3%) | 14 (30.4%) |
| Microscopic | 16 (38.1%) | 10 (21.7%) |
| Lewy bodies (any) | 11 (26.2%) | 22 (47.8%) |
| Neocortical | 7 (16.7%) | 19 (41.3%) |
| One pathology (AD, infarcts, or Lewy bodies) |
21 (50%) | 13 (28.3%) |
| Mixed pathology | 17 (40.5%) | 29 (63%) |
| FTLD or other atypical pathology |
0 | 1 (2.2%) |