Table 1.
Proteins identified by mass spectrometry were analyzed by MetaCore software (GeneGo Inc.) using two algorithms in which the output is either an intracellular signaling pathway or a biological process. Significance was defined as p<0.05.
| Pathway models | LacZ (−log P) | MyrAktl (−logP) |
|---|---|---|
| Translation: Elongation: Termination | 3.9 | (n/s) |
| Cytoskeleton: Regulation of cytoskeleton rearrangement | (n/s) | 4.7 |
| Cell cycle: Meiosis | (n/s) | 5.9 |
| Cytoskeleton: Cytoplasm microtubules | (n/s) | (n/s) |
| Inflammation: IL-6 signaling | (n/s) | 4.1 |
| DMA damage: Check point | (n/s) | 4.1 |
| Inflammation: TREMI signaling | (n/s) | 3.9 |
| Cell cycle: GI-S | (n/s) | 3.6 |
| Cell adhesion: Cell junctions | (n/s) | 3.6 |
| Transduction: Translation initiation | 4.5 | (n/s) |
| Biological process models | LacZ (−log P) | MyrAktl (−logP) |
| Glycolysis and gluconeogenesis | (n/s) | (n/s) |
| Vitamin K metabolism | (n/s) | (n/s) |
| Transcription: Role of heterochromatin protein(HPI) family in transcriptional silencing | (n/s) | 1.5 |
| Cell cycle: Role of 14-3-3 proteins in cell cycle regulation | (n/s) | 5.7 |
| Translation: Regulation of translation initiation | 1.6 | (n/s) |
| Cytoskeleton remodeling: Neurofilament | (n/s) | (n/s) |
| Glycolysis and gluconeogenesis | (n/s) | (n/s) |
| Transcription: Role of AP in regulation of cellular metabolism | (n/s) | (n/s) |
| Cell cycle: Spindle assembly and chromosome separation | (n/s) | (n/s) |
| Development: Role of CDKS in neuronal development | (n/s) | (n/s) |
n/s: not significant