Table 1. Description of Logic Modeling Variants.

logic modeling variant	time treatmenta	detail of species’ states	use in biological modeling
Boolean	discrete time steps	binary	(13, 15−17, 19, 24, 25, 33);b20, 42, 43, 51, 52c
discrete logic	discrete time steps	multistate; user-defined	(21, 31, 32, 38);b31, 53, 54c
fuzzy logic	discrete time steps or time can be treated as a variable	multistate; user-defined and implicit in calculation of output state	(14,18,30)b
piecewise linear	continuous	multistate; user-defined and implicit in equations	(42,55)c
logic-based ODEs	continuous	multistate; implicit in ODE equations	(28)b
standardized qualitative dynamical systems	continuous	multistate; implicit in formalism	(23)b

^aDiscrete time steps could use synchronous or asynchronous updating with or without delay or be examined at steady state.

^bBiochemical signaling network.

^cGenetic network.