Table 3. SLC4A2 haplotype structure and analysis: PBC patients vs. controls.
SNP |
Frequency |
P-additive (P =0.913)a |
P-dominant (P =0.775)a |
P-recessive (P =0.707)a |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | PBC | Control | |||
1 | C | G | G | A | C | G | C | G | C | G | G | C | 0.283 | 0.316 | 0.182 | 0.076 | 0.897 |
2 | C | G | A | G | C | G | C | A | C | G | G | C | 0.160 | 0.155 | 0.687 | 0.843 | 0.450 |
3 | T | A | A | A | C | G | T | G | C | A | A | C | 0.131 | 0.127 | 0.893 | 0.987 | 0.613 |
4 | C | G | A | A | C | A | C | A | C | A | G | T | 0.127 | 0.115 | 0.523 | 0.657 | 0.275 |
5 | T | A | A | A | C | G | C | G | C | A | A | C | 0.051 | 0.047 | 0.655 | 0.673 | NA |
6 | C | G | G | A | C | G | C | A | C | G | G | C | 0.039 | 0.045 | 0.807 | 0.819 | NA |
7 | C | G | A | A | C | A | C | A | C | G | G | C | 0.038 | 0.034 | 0.727 | 0.830 | NA |
8 | T | G | A | A | C | A | C | A | C | A | G | T | 0.032 | 0.028 | 0.953 | 0.957 | NA |
9 | T | A | A | A | T | G | T | G | C | A | A | C | 0.030 | 0.027 | 0.619 | 0.639 | NA |
10 | C | G | A | A | C | G | T | G | T | A | A | C | 0.023 | 0.028 | 0.572 | 0.597 | NA |
NA, not applicable; PBC, primary biliary cirrhosis; SNP, single nucleotide polymorphism.
Global P-value under the specified model.