Table 4. SNP frequencies and statistical analysis: AMA-positive vs. AMA-negative PBC patients.

#	SNP rs ID	Minor allele	Minor allele frequency		Additive model			Recessive model
			AMA+ (n =356)	AMA− (n =47)	OR (95% CI)	Pval	Pcor	OR (95% CI)	Pval	Pcor
1	rs33966546	T	0.27	0.29	1.10 (0.68–1.75)	0.711	1.000	2.38 (0.95–5.88)	0.063	0.303
2	rs2303929	A	0.23	0.28	1.27 (0.79–2.04)	0.320	0.933	3.70 (1.49–9.09)	0.005	0.030
3	rs2303930	G	0.36	0.28	0.70 (0.44–1.14)	0.152	0.655	0.64 (0.22–1.85)	0.412	0.983
4	rs3793336	G	0.16	0.27	1.96 (1.16–3.33)	0.011	0.074	4.76 (1.29–16.7)	0.018	0.091
5	rs35576067	T	0.03	0.03	0.89 (0.26–3.13)	0.859	1.000	NAa	—	—
6	rs12703112	A	0.22	0.18	0.77 (0.44–1.35)	0.359	0.957	0.39 (0.05–3.03)	0.362	0.958
7	rs13247141	T	0.21	0.17	0.80 (0.46–1.37)	0.421	0.977	0.68 (0.15–3.03)	0.605	1.000
8	rs2303933	A	0.43	0.49	1.25 (0.79–1.92)	0.303	0.924	1.89 (0.95–3.70)	0.067	0.313
9	rs2303934	T	0.04	0.01	0.29 (0.03–1.82)	0.173	0.718	NAa	—	—
10	rs2303937	A	0.45	0.41	0.86 (0.56–1.33)	0.509	0.997	1.18 (0.56–2.43)	0.669	1.000
11	rs11765015	A	0.26	0.26	0.99 (0.61–1.59)	0.962	1.000	2.13 (0.87–5.26)	0.098	0.446
12	rs11766855	T	0.18	0.15	0.73 (0.39–1.37)	0.327	0.937	NAa	—	—

AMA, antimitochondrial antibodies; CI, confidence interval; NA, not applicable; OR, odds ration; PBC, primary biliary cirrhosis; SNP, single nucleotide polymorphism.

^aAt least one of the groups had no rare allele homozygotes.