Table 1.
Genetic interaction of PLP-1 with Wnt and MAPK mutants
| Genotype | % Lacking Endoderm (n) |
|---|---|
| plp-1(RNAi) | 3 (330) |
| mom-4(or39); unc-22(RNAi) | 41 (151) |
| mom-4(or39); plp-1(RNAi) | 42 (130) |
| mom-5(or57); unc-22(RNAi) | 3 (79) |
| mom-5(or57); plp-1(RNAi) | 35 (88) |
| mom-2(or42); unc-22(RNAi) | 66 (302) |
| mom-2(or42); plp-1(RNAi) | 96 (265) |
| mom-2(or42) ;plp-1(RNAi); pop-1(RNAi) | 42 (115) |
|
mom-2(or42); unc-22(RNAi); pop- 1(RNAi) |
0 (85) |
| pop-1(zu189); plp-1(RNAi) | 0 (286) |
Percentage of arrested embryos lacking endoderm was determined for each of the indicated genotypes. unc-22, which performs no relevant role in endoderm specification, was used as a negative control for the plp-1(RNAi) experiments. The data were taken from representative experiments repeated at least twice.