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. Author manuscript; available in PMC: 2010 Dec 2.
Published in final edited form as: Cell Mol Bioeng. 2009 Dec 2;2(4):464–474. doi: 10.1007/s12195-009-0097-z

Figure 4.

Figure 4

Changes in expression of molecular structures parallel that of force generation. (A) Timecourse of actin (green) distribution on the basal surface of cells. Cells were counterstained for nuclei using DAPI (red). The outlines of cells, derived from differential interference contrast images, are added to help delineate the borders of the cell. (B) Localization of the anchorage-associated proteins paxillin (red) and β1-integrin subunit (green). (C) Fast dynamics of actin assembly, preceding the application of force to the pillar arrays. The outline indicates the boundary of a representative cell which is the focus of this time series, but additional actin-containing processes from other cells are visible in the top row. The yellow arrow indicates the same position in the two rows, corresponding to a site of contraction, as detailed in the text.