Table 3.

Association of log-transformed leptin with bone phenotypes in 1250 Chinese adolescents aged 13–21 yr, with adjustment of different body compositions

Regression models	WB-BA	L2L4-BA	TH-BA	WB-BMC	L2L4-BMC	TH-BMC	CSA	SM
Males
Basic modela	25.22 ± 6.45d	−0.16 ± 0.15	−0.16 ± 0.11	2.82 ± 5.36	0.13 ± 0.23	0.28 ± 0.20	0.01 ± 0.01	0.00 ± 0.01
Basic model+LM	23.33 ± 4.83e	−0.19 ± 0.15	−0.19 ± 0.10	4.44 ± 5.23	0.09 ± 0.23	0.18 ± 0.18	0.00 ± 0.01	0.00 ± 0.01
Basic model+BW	−25.71 ± 5.19e	−0.84 ± 0.17e	−0.69 ± 0.13e	−3.98 ± 6.28	−0.61 ± 0.27b	−0.65 ± 0.22c	−0.05 ± 0.01e	−0.03 ± 0.01d
Basic model+BMI	−25.68 ± 5.31e	−0.84 ± 0.17e	−0.70 ± 0.13e	−1.95 ± 6.27	−0.58 ± 0.27b	−0.61 ± 0.22c	−0.05 ± 0.01e	−0.03 ± 0.01d
Basic model+LM+FM	−4.18 ± 5.36	−0.21 ± 0.18	−0.17 ± 0.12	0.77 ± 6.35	−0.43 ± 0.27	−0.09 ± 0.23	−0.01 ± 0.01	−0.01 ± 0.01
Females
Basic modela	52.02 ± 8.28e	0.08 ± 0.09	0.21 ± 0.12	−5.35 ± 5.88	0.51 ± 0.25c	0.43 ± 0.22b	0.02 ± 0.01b	0.01 ± 0.01
Basic model+LM	32.96 ± 7.05e	−0.16 ± 0.19	−0.01 ± 0.11	−6.57 ± 5.86	0.28 ± 0.25	0.07 ± 0.21	0.00 ± 0.01	0.00 ± 0.00
Basic model+BW	−20.50 ± 5.67d	−0.55 ± 0.21b	−0.33 ± 0.12c	−8.44 ± 6.32	−0.24 ± 0.29	−0.60 ± 0.23c	−0.03 ± 0.01c	−0.01 ± 0.01c
Basic model+BMI	−21.71 ± 5.73d	−0.58 ± 0.21c	−0.36 ± 0.12c	−8.69 ± 6.35	−0.29 ± 0.29	−0.64 ± 0.23c	−0.03 ± 0.01c	−0.01 ± 0.01c
Basic model+LM+FM	−20.96 ± 5.88d	−0.51 ± 0.22b	−0.18 ± 0.13	−0.81 ± 6.81	−0.14 ± 0.30	−0.30 ± 0.24	−0.02 ± 0.01	−0.01 ± 0.01

Data are expressed as β (parameter estimate) ± se. LM, Whole-body LM; FM, whole-body FM; BW, body weight. 

^aBasic model adjusted for age, Tanner stage, height, menarche status (no menarche, menarche at ≤13 yr, menarche at 14 yr, menarche at ≥15 yr), physical activity, active or passive smoking (yes/no), student/nonstudent, and corresponding BA (for BMC only). 

^bP < 0.05; 

^cP < 0.01; 

^dP < 0.001; 

^eP < 0.0001.