Table 1.
Characteristics of younger and older postmenopausal subjects
| Younger | Older | P value | |
|---|---|---|---|
| Age (yr) | 53.4 (0.9) | 72.2 (0.6) | <0.001 |
| Years postmenopause | 4.1 (1.3) | 28.3 (2.8) | <0.001 |
| Years postmenopause or HRT | 3.4 (0.5) | 19.7 (5.3) | 0.008 |
| Weight (kg) | 80.6 (2.8) | 72.2 (4.1) | 0.11 |
| BMI (kg/m2) | 29.1 (0.9) | 28.5 (1.6) | 0.74 |
| Baseline | |||
| Estradiol (pg/ml)a | 20.3 (4.6) | 18.9 (3.9) | 0.81 |
| LH (IU/liter) | 69.2 (5.0) | 65.5 (10.6) | 0.76 |
| FSH (IU/liter) | 133.7 (17.4) | 99.5 (13.6) | 0.14 |
| + Estrogen | |||
| Estradiol (pg/ml)a | 58.4 (12.6) | 79.6 (29.2) | 0.52 |
| LH (IU/liter) | 46.1 (8.0) | 49.6 (9.6) | 0.78 |
| FSH (IU/liter) | 57.1 (10.3) | 59.9 (10.0) | 0.85 |
Values are expressed as mean (se). Gonadotropins are expressed in IU/liter, as equivalents of the 2nd International Reference Preparation of human menopausal gonadotropins. P values represent younger vs. older comparisons. BMI, Body mass index.
a
To convert pg/ml to pmol/liter, multiply by 3.67.