Table 1.
Patient characteristics at inclusion
| Milnacipran N = 90 | Venlafaxine N = 91 | Total N = 181 | |
|---|---|---|---|
| Males/Females | |||
| n (%) | 35 (38.9%)/55 (61.1%) | 36 (39.6%)/55 (60.4%) | 71 (39.2%)/110 (60.8%) |
| Age (years) | |||
| Mean [SD] | 44.6 [11.4] | 42.7 [12.8] | 43.7 [12.1] |
| Min/Max | 19.0/68.0 | 18.0/69.0 | 18.0/69.0 |
| BMI (kg/m2) | |||
| Mean [SD] | 24.2 [4.6] | 24.0 [4.3] | 24.1 [4.4] |
| Min/Max | 17.4/35.2 | 16.4/37.3 | 16.4/37.3 |
| N = 90 | N = 87 | N = 177 | |
| Duration of current episode (months) | |||
| Mean [SD] | 3.6 [2.8] | 3.2 [2.2] | 3.4 [2.5] |
| Min/Max | 0.0/17.0 | 0.0/15.0 | 0.0/17.0 |
| Severe episode (DSM-IV-TR) | |||
| n (%) | 57 (63.3%) | 47 (54.0%) | 104 (58.8%) |
| Suicide risk (MINI) | |||
| n (%) | 39 (43.3%) | 37 (42.5%) | 76 (42.9%) |
| Low: n (%) | 34 (37.8%) | 33 (36.3%) | 67 (37.0%) |
| Moderate: n (%) | 4 (4.4%) | 4 (4.4%) | 8 (4.4%) |
| High: n (%) | 1 (1.1%) | 0 | 1 (0.6%) |
| MADRS | |||
| Mean [SD] | 31.4 [4.6] | 30.7 [4.4] | 31.0 [4.5] |
| Min/Max | 23.0/43.0 | 23.0/43.0 | 23.0/43.0 |
| CGI-S | |||
| Mean [SD] | 5.1 [0.7] | 5.2 [0.7] | 5.2 [0.7] |
| Min/Max | 3.0/6.0 | 4.0/6.0 | 3.0/6.0 |
Abbreviations: CGI-S, Clinical Global Impression of Severity; MADRS, Montgomery-Åsberg Depression Rating Scale; SD, standard deviation.