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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Dev Biol. 2009 Nov 20;341(1):66–83. doi: 10.1016/j.ydbio.2009.10.024

Table 3. Comparison of fusion phenotypes in genes that have been analyzed in at least two model organisms.

Gene Name (Drosophila/ Vertebrate) Drosophila mouse zebrafish
wild type graphic file with name nihms155412t1.jpg graphic file with name nihms155412t1.jpg graphic file with name nihms155412t1.jpg
rac1,2, mtl/rac11 graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg
mbc/dock1, 5 graphic file with name nihms155412t2.jpg graphic file with name nihms155412t3.jpg graphic file with name nihms155412t4.jpg
graphic file with name nihms155412t5.jpg graphic file with name nihms155412t6.jpg
trio/trio graphic file with name nihms155412t1.jpg graphic file with name nihms155412t2.jpg
loner/Iqsec (Brag2)* graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg
kette/Nap1* graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg
sns, hbs/nephrin graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg
ca cdc422/cdc421 graphic file with name nihms155412t1.jpg graphic file with name nihms155412t2.jpg
crk/crk* graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg
kirre, rst/kirrel** graphic file with name nihms155412t2.jpg graphic file with name nihms155412t2.jpg
ca rac12/ca Rac graphic file with name nihms155412t2.jpg graphic file with name nihms155412t7.jpg

Key: Inline graphic no/reduced fusion Inline graphic normal fusion Inline graphic hyperfusion

1

Conditional Rac1 and Cdc42 mutant mice (Rac1fl/fl; Lbx1cre and Cdc42fl/fl; Lbc1cre);

2

Constitutively active (ca) Rac1 (Drac1V12) and Cdc42 (cdc42V12) alleles; Single and double asterisks indicate phenotype resulting from protein knockdown using shRNA or morpholinos, respectively. See text for references.