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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Biol Psychiatry. 2009 Nov 7;67(9):812–822. doi: 10.1016/j.biopsych.2009.09.016

Table 1.

Baseline Self-Administration Parameters (Mean ± SEM) Before Testing of the mGlu Receptors Compounds

Group Responses Ethanol Intake
(g/kg)
Ethanol Lever Water Lever
Ethanol Reinforcement
 Nucleus Accumbens (MPEP) 180.67 ± 44.90 20.33 ± 7.76 .96 ± .22
 Nucleus Accumbens (LY379268) 202.42 ± 40.38 6.00 ± 1.68 1.32 ± .29
 Dorsomedial Caudate (MPEP) 185.36 ± 27.93 23.86 ± 8.74 1.15 ± .18
 Medial Prefrontal Cortex (MPEP) 187.00 ± 12.46 23.40 ± 11.32 1.02 ± .08
Sucrose Reinforcement
 Nucleus Accumbens (MPEP) 171.93 ± 21.21 25.43 ± 7.83

mGlu, metabotropic glutamate; MPEP, 2-methyl-6-(phenylethynyl)pyridine hydrochloride.