Fig. 3. Knockdown of EGFP expression using lentivirus in HeLa cells.
A. HeLa cells transduced with 5 MOI of pcFUW-LUCkd-pgk-puro control vector and 1 MOI of pcFUW-EGFP cotransduced HeLa cells in light field. B. EGFP green fluoresence visualized from A. C: Morphology of HeLa cells transduced with 5 MOI of pcFUW-EGFPkd-pgk-puro and 1 MOI of control vector pcFUW-EGFP in light field. D. EGFP expression from C was silenced under fluorescence microscopy. E. EGFP expression in HeLa cells was detected by Western blot after co-transduction with 1 MOI pcFUW-EGFP with 15 MOI control vector pcFUW-miR21LUCkd-pgk-puro (I) and different MOI of EGFP knockdown viruses pcFUW-miR21EGFPkd 5(II), 10(III) and 15(IV), respectively.
