Table 4.
Examples of fungal natural products assembled in part from anthranilate (Ant).
| Compound | AA building blocks | Producer | References |
|---|---|---|---|
| Acetylaszonalenin | Ant, Trp | N. fischeri | (9) |
| 5-N-acetylardeemin | Ant, Ala, Trp | A. terreus | (69) |
| Glyantrypine | Ant, Trp, Gly | A. clavatus | (70) |
| Alantrypinone | Ant, Trp, Ala | A. terreus | (46) |
| Fumiquinazoline A | Ant, Trp, Ala + Alaa | A. fumigatus | (44) |
| Fiscalin A | Ant, Trp, Val + Alaa | N. fischeri | (71) |
| Tryptoquivaline | Ant, Trp, Val + 2-Me-Alaa | A. clavatus | (47) |
| Asperlicin | Ant, Ant, Trp + Leua | A. alliaceus | (42) |
| Benzomalvin C | Ant, Ant, Phe | Penicillium sp. | (41) |
| Circumdatin F | Ant, Ant, Ala | A. ochraceus | (72) |
| Sclerotigenin | Ant, Ant, Gly | P. sclerotigenum | (73) |
| Verrucine A | Ant, Gln, Phe | P. verrucosum | (74) |
| Auranthine | Ant, Gln, Ant | P. aurantiogriseum | (4) |
| Cyclopenin | Ant, Phe | P. cyclopium | (75) |
a
The amino acids listed before the “+” sign are postulated to form a cyclized tripeptide core structure that is further modified by incorporation of the amino acid following the “+” sign (see Figure S6B for an example).