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. Author manuscript; available in PMC: 2011 Apr 20.
Published in final edited form as: Langmuir. 2010 Apr 20;26(8):5364–5373. doi: 10.1021/la9037843

Figure 2.

Figure 2

Assessment of DiI-encapsulating HBPE nanoparticles’ cellular uptake via confocal laser-scanning microscopy. a) No internalization was observed in cells incubated with carboxylated HBPE nanoparticles (9), b) enhanced internalization was observed with folate-clicked HBPE nanoparticles (13). Cells incubated with c) Taxol-encapsulating folate HBPE nanoparticles (13) induced Taxol-mediated mitotic arrest, leading to cell death, d–f) corresponding bright field confocal images of the A549 cells treated with corresponding functional HBPE nanoparticles. Nuclei stained with DAPI (blue). These observations confirmed the targeting capability and receptor mediated internalization of our theranostic HBPE nanoparticles.