Figure 1.
Locomotor response of sexually experienced and naïve animals to saline or amphetamine administration. A is a schematic diagram of the zone map used to measure locomotor activity. A crossover is recorded each time the animal enters one of the black zones. Mean +/− SEM of total number of crossovers over 90 minutes (B) and in 30-minute intervals (C-E; C, 0–30 minutes. D, 31–60 minutes. E, 61–90 minutes). * indicates a statistically significant difference between AMPH and saline. # indicates a statistically significant difference between experience and naive groups (p < 0.05). F displays crossovers per 3-minute interval over 90-minutes (statistical differences are not indicated) (p-values: B, NA vs. NS, p = 0.0422; EA vs. ES, p < 0.0001, EA vs. NA; p < 0.0001; C–E, EA vs. NA; p < 0.001, EA vs. ES; p < 0.001; E, NA vs. NS; p = 0.0024).