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. Author manuscript; available in PMC: 2011 Apr 30.
Published in final edited form as: Toxicology. 2010 Feb 18;271(1-2):27–35. doi: 10.1016/j.tox.2010.02.009

Fig 1. Comparisons of DMBA blood levels and major metabolites after oral gavage or IP administration.

Fig 1

A) Circulating DMBA levels in blood collected by cardiac puncture at the indicated time points following oral or IP DMBA treatment (50 mg/kg). Each time point represents the mean (± SEM) of 2 to 3 different mice. B) Representative HPLC profiles of DMBA metabolites in the blood at 6 h after oral gavage (upper panel) or IP administration (lower panel). Major metabolites identified are: 5, 6-dihydrodiol, 8, 9-+10, 11-dihydrodiol, 7-OH DMBA, DMBA, DBP.