Table 1.

Summary of studies that have confirmed endogenous interactions in mammalian cells between Beclin 1 and the indicated Beclin 1-binding partners

Beclin 1-binding partner	References
A. Class III PI3K complex components
Autophagy inducers:
Vps34	[3••,9•,10•]
Vps15	[9•]
Ambra1	[12••]
Atg14	[9•,10•,11•]
UVRAG	[9•,10•,14]
Bif	[15]
Autophagy inhibitors:
Rubicon	[9•]
B. Bcl-2 family members
Bcl-2	[20••,23•,32•,33]
Bcl-XL	[36]
C. Receptor and adaptor proteins
Inositol 1,4,5-trisphosphate receptor (IP3R)	[41]
Estrogen receptor (ERα)	[45]
MyD88 and TRIF	[42]
nPIST	[43]