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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Dev Biol. 2010 Feb 6;341(1):291–304. doi: 10.1016/j.ydbio.2010.02.001

Fig. 1. Cardiac development is affected in Hand2 hypomorph embryos.

Fig. 1

Whole hearts were removed from Hand2fl/fl [A] and Hand2flneo/flneo [B] E18.5 embryos and 20 μm frozen transverse sections were visualized following staining with Hematoxylin and Eosin. Misexpression of Hand2 [B] consistently results in enlarged hypoplastic right ventricles and disorganized trabeculations. Abbreviations: right ventricle (RV), left ventricle (LV), aorta (Ao). Scale bars indicate 100 μm [A,B] and 25 m [A1,A2,B1,B2].