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The AVE does not migrate in Bmpr-null embryos
Whole mount in situ analysis for Cer1 (A, B) or Dkk1 (E, F) and the expression of Hex-GFP (C, D). Cer1 or Hex-GFP was expressed in the AVE of control embryos (A, C arrow). In Bmpr-null embryos, Cer1 and Hex expression is localized to the distal tip (B, D, arrow). Dkk1 is expressed in the PxVE at E5.5 control embryos (E, arrows), but not in Bmpr-null embryos (F). Bars=100 μm.
