TABLE 2.
BASELINE DEMOGRAPHIC AND CLINICAL VARIABLES OF 97 PATIENTS WITH BIOPSY-PROVEN IDIOPATHIC PULMONARY FIBROSIS AND 38 PATIENTS WITH NON–IDIOPATHIC PULMONARY FIBROSIS IDIOPATHIC INTERSTITIAL PNEUMONIA
| IPF (n = 97) | Non-IPF IIP (n = 38) | P Value | |
|---|---|---|---|
| Age, yr | 62 ± 9 | 52 ± 9 | <0.0001 |
| Sex, male/female | 40 (41%)/57 (59%) | 22 (58%)/16 (42%) | 0.08 |
| Smoking status, never/ever-smoker | 32 (35%)/60 (65%)* | 15 (41%)/22 (59%)† | |
| HRCT scores | |||
| HRCT alveolar score | 1.72 ± 0.95 | 2.29 ± 1.32 | 0.02 |
| HRCT interstitial score | 0.91 ± 0.29 | 0.54 ± 0.39 | <0.001 |
| Pulmonary function | |||
| FVC, % predicted | 65 ± 16 | 70 ± 19 | 0.15 |
| DlCO, % predicted | 48 ± 17 | 50 ± 17 | 0.57 |
| 6MWT | |||
| Distance walked, ft | 911 ± 473 | 895 ± 578 | 0.92 |
| Desaturation < 88%‡ | 45 (46%) | 6 (16%) | 0.47 |
Definition of abbreviations: DlCO = diffusion capacity for carbon monoxide; HRCT = high-resolution computed tomography; IIP = idiopathic interstitial pneumonia; IPF = idiopathic pulmonary fibrosis; 6MWT = 6-minute walk test.
All patients had an HRCT interstitial score less than 2 in all lobes.
*
Missing data for five patients.
†
Missing data for one patient.
‡
Number of patients whose oxygen saturation fell below 88% during the 6MWT.