Table 1.
Distribution of case patients and control subjects by selected variables
| Variable | Former smokers |
Current smokers |
||||
|---|---|---|---|---|---|---|
| Case patients (n = 375) | Control subjects (n = 371) | P | Case patients (n = 350) | Control subjects (n = 244) | P | |
| Sex | ||||||
| Male | 222 (59.20) | 232 (62.53) | 181 (51.71) | 125 (51.23) | ||
| Female | 153 (40.80) | 139 (37.47) | 0.351 | 169 (48.29) | 119 (48.77) | 0.907 |
| Age | ||||||
| Mean (SD) | 64.8 (8.9) | 62.5 (9.7) | 0.001 | 58.0 (10.1) | 58.5 (9.4) | 0.495 |
| Pack-year | ||||||
| Mean (SD) | 48.7 (31.5) | 42.3 (31.1) | 0.005 | 57.6 (29.0) | 47.5 (29.0) | <0.001 |
| DNA repair (DRC), % | ||||||
| Mean (SD) | 8.2 (2.6) | 9.0 (3.5) | <0.001 | 8.3 (2.9) | 9.2 (3.6) | 0.002 |
| Median (range) | 8.0 (0.35–17.63) | 8.6 (2.39–23.95) | 8.1 (2.78–25.55) | 8.7 (2.09–27.21) | ||
| Bleomycin sensitivity, breaks/cell | ||||||
| Mean (SD) | 0.8 (0.4) | 0.7 (0.4) | <0.001 | 0.7 (0.4) | 0.6 (0.3) | <0.001 |
| Median (range) | 0.7 (0.10–3.24) | 0.6 (0.08–2.36) | 0.7 (0.04–2.74) | 0.5 (0.02–2.34) | ||
Abbreviation: DRC, DNA repair capacity.