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. Author manuscript; available in PMC: 2010 Apr 14.
Published in final edited form as: Sci Signal. 2009 Nov 17;2(97):ra74. doi: 10.1126/scisignal.2000374

Fig. 5.

Fig. 5

Expression of PDNF in the cytosol of Schwann cells augments transcription of the gene encoding Akt and reduces the transcription of genes encoding proapoptotic factors. (A) Results from microarray analyses are expressed as the ratio of signals from mRNA isolated from Sc-PDNF cells to those of Sc-Red cells. This experiment was repeated twice with similar results. PKA, protein kinase A; PKCβ, protein kinase Cβ; CMK2, cytidine mono-kinase 2; Tousled, tousled kinase. (B) qPCR analysis of the expression of the genes encoding the three isoforms of Akt in Sc-Red cells and Sc-PDNF cells. Results represent the ratio of Akt mRNA relative to that of hypoxanthine-guanine phosphoribosyltransferase (HPRT). Results are presented as the mean ± SD of four independent experiments. **P < 0.05.