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. Author manuscript; available in PMC: 2010 Apr 14.

Published in final edited form as: Biochemistry. 2008 May 23;47(24):6322–6328. doi: 10.1021/bi800075c

Table 3.

Summary of pK_a Values for Wild-Type and Mutant HiSAT

	pK_a ± SE
enzyme	V₁	V₁/K_Ser	V₁/K_AcCoA
wild type^a	6.8 ± 0.2	7.2 ± 0.2	N/A
H154N	6.7 ± 0.2	7.4 ± 0.4	N/A
H189N	7.5 ± 0.2	8.0 ± 0.3	N/A
D139N	6.2 ± 0.4	6.1 ± 0.5	7.2 ± 0.3 8.1 ± 0.2
H154N/H189N	N/A	7.8 ± 0.1	N/A

^a

From Johnson et al. (7).