Table 1.

Results of the various biomarkers and variables from the CGMS data. All values are expressed as means ± standard deviation. To convert mg/dL of glucose to mmol/L multiply by 18 or divide by 0.055

Interstitial Fluid Glucose values and Biomarkers	Day 2 (24–48 Hrs.)	Day 3 (48–72 Hrs.)	Day 4 (72–96 Hrs.)	Day 5 (96–100 Hrs.)	P value for the Trend
Avg. daily glucose (mg/dL)	122.7 ± 21.8	143.7 ± 19.4	154.6 ± 26.3	163.9 ± 31.8	0.001
Avg. fasting glucose (mg/dL)	120.3 ± 15.1	135.5 ± 5.2	142.8 ± 7.2	154.5 ± 33.4	0.038
Avg. 2 hour post-prandial glucose (mg/dL)	114.6 ± 24.7	149.3 ± 18.9	153.2 ± 15.1	172.1 ± 37.1	0.000
Avg. daily maximum glucose (mg/dL)	207.7 ± 44.6	249.8 ± 37.1	258.3 ± 34.7	242.8 ± 37.8	0.002
Percentage of time glucose > 180 mg/dL	14.5 ± 12.8	24.3 ± 13.2	31.8 ± 18.6	38.3 ± 24.1	0.003
1,5 anhydrodiglucitol (microgram/ml)		5.8 ± 3.8	5.9 ± 3.8	6.2 ± 3.8	.021
Carboxymethyllysine (microgram/ml)		5.7 ± 1.1	5.8 ± 1.2	5.9 ± 1.3	.517
Isoprostane (picogram/ml)		6.9 ± 2.5	6.1 ± 2.2	6.5 ± 2.2	.55