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. 2010 Apr 14;5(4):e10162. doi: 10.1371/journal.pone.0010162

Table 1. List of modules where miRNAs have been selected as high-scoring regulators.

Module ID Number of genes in the module GO categories enriched for the module (p<0.05) Regulators Score
15 73 None MAFB 3065
NFIB 2774
MSRB2 713
IGFALS 464
NR2C1 457
CCL23 392
MORF4L1 288
FOS 249
let-7c 231
miR-125b 209
17 17 Digestion NFIB 3785
Proteolysis HEYL 2361
Lipid catabolic process PLA2G1B 2164
miR-216 1085
CCRL2 780
MC5R 327
TRAF1 285
CDX1 261
DLX2 254
E2F1 251
IFNGR1 250
CCR9 244
TACR3 215
18 6 Immune response HOXC5 1937
HMGA1 1007
miR-142-5p 863
miR-142-3p 709
HLA-DRB1 380
CCL5 241
AXL 215
CXCL14 214
25 9 None miR-200a 1786
PPP1R1B 727
GPR30 512
PTGER3 456
ZNF157 320
GNB3 262
GNG5 209
29 4 Actomyosin structure organization and biogenesis PPP1R12B 7346
Smooth muscle contraction miR-133a 1216
Smooth muscle fiber development TSC22D1 1209
Elastic fiber assembly ANGPTL2 353
Striated muscle development miR-145 220
35 20 None NFATC1 2827
SH3BP1 2162
FMNL2 699
RASSF4 381
GNAQ 290
CTNNBIP1 288
miR-181* 249
94 3 Folic acid metabolic process miR-10a 253
Regulation of Notch signaling pathway
Folic acid transport

All regulators that are above cutoff are listed for each module, and ordered according to their decreasing score value. MicroRNA genes are highlighted in bold.