Table 3.

RRs considering certainty of in utero and early-life exposures in uterine fibroid associations among non-Hispanic whites, 35–59 years of age, in the Sister Study, 2003–2007.^a

	Definite				Probable
Exposure	n	No. of cases	aRRb	95% CI	n	No. of cases	aRRb	95% CI
Worked and lived on farmc	970	80	1.02	0.82–1.27	618	52	1.04	0.79–1.35
Smoking during pregnancy	5,040	368	0.97	0.87–1.10	1,853	161	1.14	0.97–1.34
DES use	404	31	1.04	0.74–1.46	239	37	2.07	1.53–2.80
Prepregnancy diabetes	29	5	2.26	1.02–5.01	35	5	1.88	0.83–4.23
Gestational diabetesd	50	2	0.60	0.15–2.33	51	7	1.88	0.94–3.74
Preeclampsia/eclampsia	248	22	1.15	0.77–1.72	142	14	1.28	0.78–2.11
Pregnancy-related hypertensione	115	11	1.30	0.74–2.28	128	9	0.96	0.51–1.80
Fed breast milk	6,356	462	0.92	0.83–1.03	811	64	0.99	0.77–1.26
Fed soy formula	481	46	1.32	1.00–1.75	160	12	1.03	0.60–1.78

aRR, adjusted risk ratio.

^aFibroids status based on self-report of diagnosis at ≤ 35 years of age, excluding 89 women missing fibroid status or age at diagnosis or who reported childhood or adolescent ages at diagnosis (< 15 years).

^bEach model included the following covariates: participant’s age and education, maternal age, firstborn status, and childhood family income (n = 19,531). The reference group is women who reported probably not or definitely not for each exposure.

^cExcludes from the reference group those reporting mothers who worked or lived on a farm (but not both) during pregnancy (n = 949).

^dExcludes those reporting mothers who definitely or probably had diabetes before pregnancy.

^eExcludes those reporting mothers who definitely or probably had preeclampsia during pregnancy.