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. 2009 Oct 23;118(3):437–443. doi: 10.1289/ehp.0900731

Table 4.

Regression coefficients and 95% confidence intervals for Hg level associated with birth weight according to GSTM1/GSTT1 genotype.

Exposure period of total Hg (log scale of μg/L) Genotype Adjusteda
Unadjusted
Full sample
Subsample excluding preterm births
β 95% CI β 95% CI β 95% CI
Early pregnancy Total −4.4 −79.5 to 70.8 −68.6 −138.6 to 1.5 −51.4 −122.2 to 19.5
GSTM1 present 66.8 −55.6 to 189.2 −37.5 −154.6 to 79.7 −37.8 −155.4 to 79.8
GSTM1 null −48.3 −143.9 to 7.3 −79.5 −168.9 to 9.9 −47.9 −138.8 to 43.0
GSTT1 present 9.1 −109.7 to 128.0 −50.7 −158.7 to 57.3 −24.0 −137.8 to 89.9
GSTT1 null −13.7 −110.2 to 82.7 −70.2 −166.5 to 26.0 −63.8 −157.9 to 30.3
Late pregnancy Total −27.1 −103.1 to 49.0 −65.5 −135.6 to 4.5 −40.1 −110.9 to 30.0
GSTM1 present 39.2 −89.1 to 167.5 −34.3 −153.7 to 85.1 −22.7 −144.6 to 99.3
GSTM1 null −64.4 −159.3 to 30.4 −84.8 −171.4 to 1.7 −57.3 −143.8 to 29.3
GSTT1 present 3.3 −124.6 to 131.1 −25.6 −140.4 to 89.2 −5.7 −122.4 to 111.0
GSTT1 null −49.1 −142.1 to 44.0 −99.0 −189.2 to −8.8 −66.8 −156.7 to 23.1
Cord blood Total −33.0 −116.1 to 49.9 −86.4 −163.1 to −9.7 −65.2 −143.0 to 12.5
GSTM1 Present 54.9 −88.9 to 198.6 −68.3 −206.6 to 70.1 −59.6 −199.5 to 80.3
GSTM1 null −78.5 −180.5 to 23.5 −107.3 −199.7 to −14.8 −74.7 −168.5 to 19.2
GSTT1 Present −39.5 −162.2 to 83.1 −77.7 −187.6 to 32.3 −54.9 −168.2 to 58.4
GSTT1 null −30.5 −144.3 to 83.4 −101.0 −212.3 to 10.4 −76.5 −187.6 to 34.6
a

Multivariate regression models included gestational age, prepregnancy BMI, maternal age, mother’s educational level, infant sex, parity, and weight gain during pregnancy as covariates.