Table 4.
Exposure period of total Hg (log scale of μg/L) | Genotype | Adjusteda |
|||||
---|---|---|---|---|---|---|---|
Unadjusted |
Full sample |
Subsample excluding preterm births |
|||||
β | 95% CI | β | 95% CI | β | 95% CI | ||
Early pregnancy | Total | −4.4 | −79.5 to 70.8 | −68.6 | −138.6 to 1.5 | −51.4 | −122.2 to 19.5 |
GSTM1 present | 66.8 | −55.6 to 189.2 | −37.5 | −154.6 to 79.7 | −37.8 | −155.4 to 79.8 | |
GSTM1 null | −48.3 | −143.9 to 7.3 | −79.5 | −168.9 to 9.9 | −47.9 | −138.8 to 43.0 | |
GSTT1 present | 9.1 | −109.7 to 128.0 | −50.7 | −158.7 to 57.3 | −24.0 | −137.8 to 89.9 | |
GSTT1 null | −13.7 | −110.2 to 82.7 | −70.2 | −166.5 to 26.0 | −63.8 | −157.9 to 30.3 | |
Late pregnancy | Total | −27.1 | −103.1 to 49.0 | −65.5 | −135.6 to 4.5 | −40.1 | −110.9 to 30.0 |
GSTM1 present | 39.2 | −89.1 to 167.5 | −34.3 | −153.7 to 85.1 | −22.7 | −144.6 to 99.3 | |
GSTM1 null | −64.4 | −159.3 to 30.4 | −84.8 | −171.4 to 1.7 | −57.3 | −143.8 to 29.3 | |
GSTT1 present | 3.3 | −124.6 to 131.1 | −25.6 | −140.4 to 89.2 | −5.7 | −122.4 to 111.0 | |
GSTT1 null | −49.1 | −142.1 to 44.0 | −99.0 | −189.2 to −8.8 | −66.8 | −156.7 to 23.1 | |
Cord blood | Total | −33.0 | −116.1 to 49.9 | −86.4 | −163.1 to −9.7 | −65.2 | −143.0 to 12.5 |
GSTM1 Present | 54.9 | −88.9 to 198.6 | −68.3 | −206.6 to 70.1 | −59.6 | −199.5 to 80.3 | |
GSTM1 null | −78.5 | −180.5 to 23.5 | −107.3 | −199.7 to −14.8 | −74.7 | −168.5 to 19.2 | |
GSTT1 Present | −39.5 | −162.2 to 83.1 | −77.7 | −187.6 to 32.3 | −54.9 | −168.2 to 58.4 | |
GSTT1 null | −30.5 | −144.3 to 83.4 | −101.0 | −212.3 to 10.4 | −76.5 | −187.6 to 34.6 |
Multivariate regression models included gestational age, prepregnancy BMI, maternal age, mother’s educational level, infant sex, parity, and weight gain during pregnancy as covariates.