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Alternative sugar binding in the active site of the glmS ribozyme. A. The Glc6P bound active site of the glmS ribozyme superimposed on the GlcN6P bound active site. The Glc6P bound structure is shown in dark shades and the GlcN6P bound structure is shown in light shades. B. The MaN6P bound active site of the glmS ribozyme superimposed on the GlcN6P bound active site. The MaN6P bound structure is shown in dark shades and the GlcN6P bound structure is shown in light shades.
