Table 1.
Description of the analyzed samples and clinical features of MS patients
| Controls | MS patients | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Samples | N | N | Age at Onsetb | Female:Male Ratio | EDSS % | Disease Course % | |||||
| <3 | 3 to <6 | ≥6 | RR | SP | PP | PR | |||||
| Italy | 628 | 827 | 32.5±10.5 | 2:1 | 53 | 28 | 19 | 76 | 12 | 10 | 2 |
| UK | 10029a | 2210 | 29.8±9.4 | 2.7:1 | 30 | 26 | 44 | 59 | 31 | 10 | 0 |
Notes: MS: Multiple Sclerosis; EDSS: Expanded Disability Status Scale (Kurtzke, 1983); RR: Relapsing Remitting; SP: Secondary Progressive; PP: Primary Progressive; PR: Progressive Relapsing.
Controls included in the paper by Nejentsev et al. (Nejentsev et al., 2009), with the exception of 467 new samples.
Mean ± Standard Deviation.