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. 2005 Apr 30;1(1):81–91. doi: 10.3988/jcn.2005.1.1.81

Figure 1.

Figure 1

Effect of NO scavengers on cell death due to SNAP. PC12 cells were treated with 500 µM SNAP in the presence of caspase inhibitors (40 µM z-LEHD.fmk [LEHD], 40 µM z-DQMD.fmk [DQMD]) or antioxidants (1 mM N-acetylcysteine [NAC], 1 mM dithiothreitol [DTT], 100 µM melatonin, 25 µM carboxy-PTIO [PTIO] and 250 µM uric acid) for 24 hours at 37℃ and mixtures were treated with 0.5 mg/ml MTT for 2 hours. Data are expressed as the percentage of control and represent means±SEM of 6 replicate values in two separate experiments. †P<0.05, compared to control. *P<0.05, compared to SNAP alone.