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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Prostate. 2008 Dec 1;68(16):1743–1752. doi: 10.1002/pros.20837

Fig. 1.

Fig. 1

Effect of 2DG on prostate cancer cell viability. LNCaP and PC-3 cells were treated with various concentrations of 2DG over 72 hr and assessed by cell counts with trypan blue (A) and MTT assay (B). Both LNCaP cells and PC-3 cells were inhibited by 2DG in a dose dependent fashion. Experiments were performed in triplicate ±SEM. To determine the effect of 2DG on cellular morphology, morphological changes in PC-3 cells were observed with time-lapse microscopy (100×) (C). Cells were treated with vehicle (Control), no glucose in media (except that contained in added serum), 5 and 25 mM 2DG over 5 days.