Table 2.
Genotype frequencies of TNFα among cases and controls and the association with AP risk. ORs with 95% CI and P-values were calculated for wild/wild genotype versus wild/mutant and mutant/mutant genotypes.
| TNFα polymorphisms | Genotype | Cases (%) n = 103 | Controls (%) n = 92 | OR (95% CI)* | P-value |
|---|---|---|---|---|---|
| TNFα −308G > A rs1800629 | GG | 15 (14.6) | 21 (22.8) | GG versus any A | .145 |
| GA | 43 (41.8) | 34 (37.0) | 1.63 (1.13−4.01) | ||
| AA | 45 (43.7) | 37 (40.2) | |||
|
| |||||
| TNFα −238G > A rs361525 | GG | 90 (87.4) | 73 (79.4) | GG versus any A | .175 |
| GA | 8 (7.8) | 18 (19.6) | 0.86 (0.75−1.77) | ||
| AA | 5 (4.9) | 1 (1.1) | |||
*OR: odds ratio; CI: 95% confidence interval; OR adjusted for age, sex, BMI, smoking status for logistic regression analysis.