Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mode of action of various molecules targeting TLR4.
| Molecules interfering with TLR4 and TLR4-mRNA expression |
| (1) Chloroquine |
| (2) Ketamine |
| (3) GTS21 (nicotinic analogue) |
| (4) Statins |
| (5) Vitamin D3 (?) |
| (6) Lidocaine |
| (7) Glycine |
|
|
| Molecules interfering with TLR4-related intracellular signalling pathway |
| (1) Eritoran (E5564) |
| (2) Resatorvid (TAK242) |
| (3) Ketamine |
| (4) Opioids |
| (5) Vitamin D3 (through its action on LL37) |
| (6) Lansoprazole (through its action on SOCS1) |
