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Quantitative determination of (a) activated HIF-α protein and (b) HIF-α mRNA and (c) VEGF protein in the gastrocnemius muscle of wild-type (WT) and Epo-TAgh mice in normoxia (Nx) and following acute hypoxia for 24 hours (AHx) and chronic hypoxia for 14 days (CHx). Values are means ± SD. *, significantly different from corresponding Nx group, P < .01. #, significantly different from corresponding WT group, P < .05. &, significantly different from corresponding AHx group. #, P < .05.
