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. Author manuscript; available in PMC: 2011 Mar 5.
Published in final edited form as: Circ Res. 2009 Dec 31;106(4):739–747. doi: 10.1161/CIRCRESAHA.109.206763

Figure 5.

Figure 5

Similar properties and densities of whole-cell LTCC currents are observed in SMCs of rat MA and MV. (A) Current-voltage (I–V) relationships for Ca2+ channel currents in MA and MV reveal similar current densities (n = 14, 7). (B) Voltage-dependent activation and inactivation were not significantly different between SMCs of MA (n = 9, 14) and MV (n = 5, 9). (C–E) Arterial SMCs treated with nifedipine (Nif, 100 nmol/L) showed a 56% reduction in LTCC channel current density (n = 9–14). (F–H) Venous SMCs showed a similar level of nifedipine–induced block of 55% (n = 4–7). * = significant difference from control (Con) in the same preparation (p<0.05).