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. 2010 Mar 17;30(11):3912–3923. doi: 10.1523/JNEUROSCI.6256-09.2010

Figure 4.

Figure 4.

Temperature alters decay time and peak current but does not alter in vivo estradiol-dependent diurnal modulation of calcium current. A–C, Average maximal current (at +10 mV) curve of cells from OVX mice, OVX+E mice in A.M. and OVX+E mice in P.M., respectively, at 25 and 32°C (gray) and 25°C scaled to compare kinetics (scaled 25). D, The amplitude of ICa is greater at 32°C than 25°C in cells from both OVX and OVX+E mice, but estradiol-dependent effects persist at both temperatures. E, F, Mean ± SEM effects of temperature on V1/2act and V1/2inact in cells from OVX and OVX+E mice in the A.M. and (*p < 0.05, OVX vs OVX+E; #p < 0.05, OVX+E A.M. vs OVX+E P.M.). G, H, Mean ± SEM effects of temperature on rise time (10–90%) and decay time (90–50%) in cells from OVX and OVX+E mice in the A.M. and P.M. (*p < 0.05, OVX vs OVX+E; #p < 0.05, OVX+E A.M. vs OVX+E P.M.).