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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Virology (Auckl). 2008 Mar 3;1:9–15. doi: 10.4137/vrt.s563

Table 1.

TUCH rotavirus VP6 aa sequences that were associated with cytokine production.

Position (TUCH) Sequence Suggested function
aa 241–255 …..Inline graphic….. Mouse CD4+ T cell epitope*
aa 281–295 …..IARNFDTIRLSFQLL…..
aa 285–299 …..FDTIRLSFQLLRPPN…..
aa 289–303 …..Inline graphic….. Mouse CD4+ T cell epitope*
aa 293–307 …..Inline graphic…..
aa 297–311 …..Inline graphic…..
aa 301–315 …..Inline graphic….. Macaque CD4+ T cell epitope
aa 305–319 …..Inline graphic…..
aa 309–323 …..Inline graphic…..
aa 313–327 …..Inline graphic…..
aa 317–331 …..HATVGLTLRIDSAVC…..
aa 321–335 …..GLTLRIDSAVCESVL…..
aa 325–339 …..RIDSAVCESVLADAN…..

The IFN-γ-associated sequence (blue bold-underlined) corresponds to a TUCH rotavirus VP6301–315 while TNF-associated region (VP6293–327) is underlined, including the IFN-γ region. Partially modified sequences (1 aa mismatch in red) of BALB/c mouse VP6 epitopes that were used as controls (McNeal et al. 2007*, Banos et al. 1997†, and Jaimes et al. 2005†) are indicated.