TABLE 1. Smooth Muscle Development Related Gene Expression Profiles in the Mouse Embryonic Bladder Mesenchyme.
| Bladder mesenchyme | E12.5 | E13.5 | > smooth muscle differentiation< | E15 | E16 |
|---|---|---|---|---|---|
| Peripheral (Layer a) |
- | SMAA TGF-β1 Gli1 |
Smooth muscle layer (layer a1) |
SMAA | SMAA |
| SM-MHC Gli1 Bmp4 SRF TGF-β1 |
Bmp4 | ||||
|
| |||||
| Loosely organized layer (Layer a2) |
SMAA | SMAA | |||
| Bmp4 | Bmp4 | ||||
|
| |||||
| Submucosa (layer b) |
Ptc1 | Gli1 | TGF-β1 | Ptc1 | |
| Gli1 | Bmp4 | Bmp4 | |||
| Bmp4 | |||||