TABLE 1.

Effect of alcohol on plasma concentrations of BCAA, insulin, and IGF-I in WT and BCATm KO mice¹²

	Saline		Alcohol		P-value
	WT	BCATm KO	WT	BCATm KO	Genotype	Alcohol	Genotype × alcohol
Leucine, μmol/L	58 ± 10	847 ± 164	111 ± 31	835 ± 144	<0.0001	>0.1	>0.1
Isoleucine, μmol/L	87 ± 10	602 ± 104	97 ± 16	674 ± 139	<0.0001	>0.1	>0.1
Valine, μmol/L	144 ± 39	772 ± 226	162 ± 33	792 ± 258	<0.0001	>0.1	>0.1
Insulin, pmol/L	134 ± 18	77 ± 8	145 ± 23	81 ± 11	<0.001	>0.1	>0.1
IGF-I, pmol/L	110 ± 11	98 ± 12	91 ± 12	89 ± 10	>0.1	>0.1	>0.1

¹Values are means ± SEM, n = 8–10.

²Food was removed from mice at 0700 h and blood was collected between 0900 and 1200 h.