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Changes in the percent methylated cytosine in folate-compromised Mexican-American men grouped by choline intake and MTHFR C677T genotype. Data are presented as estimated marginal means ± SEM (n = 6–7/group) and were analyzed by linear regression. Because choline intake interacted with the MTHFR genotype (P = 0.021), the regression analysis was repeated separately for each genotype. Labeled means without a common letter differ, P < 0.05.
