TABLE 3.
OR (95% CI) | P-value | Model r2 | Model adjusted r2 | |
---|---|---|---|---|
White women | ||||
Model 1 | 2.6 | 3.8 | ||
rs11168292 | 1.8 (1.1, 3.0) | 0.02 | ||
Model 2 | 8.0 | 12.0 | ||
rs11168292 | 1.7 (1.1, 2.8) | 0.04 | ||
Serum 25(OH)D at <22 wk | ||||
<37.5 nmol/L | 14.0 (2.7, 73.0) | 0.005 | ||
37.5–75 nmol/L | 1.0 (ref) | |||
>75 nmol/L | 2.0 (1.1, 3.7) | 0.17 | ||
Black women | ||||
Model 1 | 12.3 | 18.6 | ||
rs11168287 | 0.4 (0.2, 0.9) | 0.03 | ||
rs3782905 | 5.7 (1.8, 17.7) | 0.004 | ||
rs2239179 | 0.3 (0.1, 0.6) | 0.003 | ||
Model 2 | 14.0 | 21.0 | ||
rs11168287 | 0.4 (0.2, 0.8) | 0.02 | ||
rs3782905 | 5.3 (1.8, 17.4) | 0.003 | ||
rs2239179 | 0.3 (0.1, 0.7) | 0.004 | ||
Serum 25(OH)D at <22 wk | ||||
<37.5 nmol/L | 1.4 (0.5, 3.9) | 0.61 | ||
37.5–75 nmol/L | 1.0 (ref) | |||
>75 nmol/L | 3.4 (0.6, 17.4) | 0.18 |
Additive models were analyzed for each SNP. OR represent the increase in odds associated with the addition of 1 allele.