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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Anticancer Drugs. 2009 Jul;20(6):444–449. doi: 10.1097/CAD.0b013e32832afc04

Table 1.

IC50 (μmol/l) of FLLL11, FLLL12, and curcumin in human pancreatic cancer cells and normal human cells

FLLL11 FLLL12 Curcumin
λPANC-1 3.20 3.09 20.35
BXPC-3 0.28 1.31 8.67
MIA-PACA-2 2.52 3.43 11.16
ASPC-1 0.95 2.64 12.40
HPAC 0.50 0.91 15.99
HPDE 0.44 0.26 5.60
Bladder 206.41 886.76 >1000

Pancreatic cancer cells or normal human cells were seeded in 96-well plates (4000λcells/well) in triplicate. The next day, pancreatic caner cells were treated with FLLL11, FLLL12, and curcumin for 72λh. The cell viability was analyzed by MTT assays. IC50 values were calculated using Sigma Plot from two to three independent experiments with each dose of drug in triplicate well.