Table 1.

Basal values of mean arterial pressure, renal hemodynamics and electrolyte excretion of the left kidney in sham-operated rats and in nonclipped kidneys of 2K1C rats.

Group	n	MAP mmHg	GFR ml.min−1.g−1	RPF ml.min−1.g−1	UNaV µmol.min−1.g−1	FENa %	V µl.min−1.g−1
7-Sham-operated + i.r. saline	11	119 ± 3	0.79 ± 0.07	2.34 ± 0.24	1.13 ± 0.14	0.97 ± 0.19	12.6 ± 0.8
7-Sham-operated + i.r. MS-PPOH	16	123 ± 3	0.81 ± 0.08	2.28 ± 0.21	1.18 ± 0.19	0.95 ± 0.18	12.9 ± 0.6
7-Sham-operated + i.r. DDMS	15	122 ± 2	0.76 ± 0.09	2.31 ± 0.19	1.21 ± 0.17	0.94 ± 0.09	12.7 ± 0.7
27-Sham-operated + i.r. saline	11	121 ± 4	0.82 ± 0.08	2.22 ± 0.18	1.15 ± 0.21	0.96 ± 0.12	11.6 ± 0.8
27-Sham-operated + i.r. MS-PPOH	16	123 ± 4	0.77 ± 0.06	2.36 ± 0.25	1.19 ± 0.26	0.88 ± 0.11	11.9 ± 0.7
27-Sham-operated + i.r. DDMS	16	120 ± 3	0.82 ± 0.07	2.28 ± 0.21	1.21 ± 0.29	0.84 ± 0.14	12.1 ± 0.8
7-2K1C + i.r. saline	11	145 ± 4*	0.75 ± 0.07	2.14 ± 0.14	1.41 ± 0.24	1.01 ± 0.17	12.4 ± 0.5
7-2K1C + i.r. MS-PPOH	16	147 ± 5*	0.76 ± 0.05	2.19 ± 0.18	1.38 ± 0.28	1.09 ± 0.16	12.8 ± 0.6
7-2K1C + i.r. DDMS	16	148 ± 4*	0.77 ± 0.06	2.17 ± 0.20	1.42 ± 0.18	1.07 ± 0.25	12.2 ± 0.7
27-2K1C + i.r. saline	11	162 ± 3#	0.74 ± 0.08	2.27 ± 0.22	1.39 ± 0.19	1.03 ± 0.19	12.9 ± 0.9
27-2K1C + i.r. MS-PPOH	15	161 ± 3#	0.75 ± 0.06	2.32 ± 0.19	1.27 ± 0.16	1.07 ± 0.26	11.8 ± 0.7
27-2K1C + i.r. DDMS	15	162 ± 4#	0.77 ± 0.07	2.21 ± 0.18	1.31 ± 0.28	1.01 ± 0.15	11.9 ± 0.6

Abbreviations are: 2K1C, 2-kidney, 1-clip Goldblatt hypertensive rats; , 7, 27 - seven or 27 days after clip placement (or sham operation) MAP, mean arterial pressure; GFR, glomerular filtration rate; RPF, renal plasma flow; U_NaV, absolute sodium excretion; FE_Na, fractional sodium excretion; V, urine flow.

^*P<0.05 versus the corresponding values in sham-operated rats ;

^#P<0.05 versus the corresponding values in 7day-2K1C rats and in sham-operated rats