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. Author manuscript; available in PMC: 2011 Apr 22.
Published in final edited form as: J Med Chem. 2010 Apr 22;53(8):3013–3027. doi: 10.1021/jm9012938

Figure 4.

Figure 4

World map illustrating the global spread of KPC enzymes. A blank world map was obtained from http://upload.wikimedia.org/ and countries with KPC occurences were colored in different opacities of red (symbolizing SBLs) according to the number of publications found on PubMed at http://www.ncbi.nlm.nih.gov/. Publications were retrieved using search strings such as “KPC-* United States” and titles and abstracts were checked for content. Only articles reporting occurences of KPCs were included, while review articles and reports restricted to computational and/or in vitro studies were excluded. Countries, for which ten or more publications with KPC reports were found, were colored in red with 100% opacity; those with fewer publications with lower opacities: 7-9 publications, 80%; 4-6 publications, 60%; 1-3 publications, 40%; no publications, white (see color code in the Figure). For more details see Supporting Information S2-S3.